Chemical Name: Pentylene Glycol
Synonyms: 1,2-Pentanediol; 1,2-Dihydroxypentane
CAS Number: 5343-92-0
Recommended Use: Solvent, cosmetic ingredient, humectant in skincare products
Manufacturer Identification: Supplied by multiple global chemical manufacturers
Emergency Contact: Refer to supplier emergency telephone number
Classification: Not classified as hazardous according to OSHA or GHS criteria
Label Elements: Not required for this substance due to low acute toxicity
Signal Word: None
Hazard Statements: May cause mild transient irritation on contact with eyes or skin
Precautionary Statements: Wash hands after handling, avoid prolonged exposure
Potential Health Effects: Irritation to eyes, slight skin discomfort after repeated contact, not sensitizing, minimal inhalation risk under normal conditions of use
Chemical Name: 1,2-Pentanediol
Synonyms: Pentylene Glycol
CAS Number: 5343-92-0
Concentration: ≥ 98% purity
Impurities: Trace (<1%) unreacted starting materials or minor byproducts
Inhalation: Move victim to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash with plenty of water and mild soap, remove contaminated clothing
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, keep eyes wide open while rinsing
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice in case of discomfort
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Special Hazards: Combustion releases carbon oxides (CO, CO2) and potentially irritating fumes
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing
Advice for Firefighters: Approach from upwind, use water spray to cool containers exposed to fire
Explosion Data: No known significant explosion hazards at typical use concentrations
Personal Precautions: Wear gloves, goggles, and protective clothing to prevent contact
Environmental Precautions: Prevent large quantities from entering drains, soil, or waterways
Method for Cleaning Up: Absorb spill with inert material such as sand or earth, collect into containers for disposal, clean contaminated surfaces with water and detergent
Reference to Other Sections: Refer to exposure controls and personal protection guidance below
Safe Handling: Avoid eye and prolonged skin contact, use in well-ventilated area, keep container closed when not in use
Storage Conditions: Store in tightly sealed containers, keep in a cool, dry, well-ventilated space away from direct sunlight and ignition sources
Incompatible Materials: Strong oxidizing agents, strong acids
Hygiene Requirements: Wash hands thoroughly after handling; do not eat, drink, or smoke around the material
Occupational Exposure Limits: No established exposure limits for pentylene glycol
Engineering Controls: General room ventilation sufficient for normal handling, local exhaust if used in confined spaces
Personal Protective Equipment: Chemical-resistant gloves, safety glasses or goggles, lab coat or protective clothing
Respiratory Protection: Not required for normal usage conditions, use approved respirator if mist or vapors are generated
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, characteristic
Odor Threshold: Not determined
pH: 6.0 - 8.0 (100 g/L, 20°C)
Melting Point/Freezing Point: -5 to -2°C
Boiling Point: 210 - 215°C
Flash Point: 121°C (closed cup)
Evaporation Rate: Negligible at ambient conditions
Flammability: Not highly flammable, but can support combustion at elevated temperatures
Vapor Pressure: <0.01 hPa at 20°C
Vapor Density: Heavier than air
Relative Density: 0.990 - 1.000 g/cm³ at 20°C
Solubility: Miscible with water, soluble in many organic solvents
Partition Coefficient (n-octanol/water): log Kow = 0.2 - 0.6
Auto-ignition Temperature: Approx. 285°C
Decomposition Temperature: >200°C
Viscosity: 33 mPa·s at 25°C
Chemical Stability: Stable under normal conditions and temperatures
Reactivity: Low reactivity at room temperature
Hazardous Reactions: No hazardous polymerization likely
Conditions to Avoid: Strong heat, sources of ignition, prolonged exposure to light
Incompatible Materials: Strong oxidizers, acids, some metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating organic vapors at high temperatures
Acute Toxicity: Oral LD50 (rat): approx. 4,000 mg/kg, low toxicity
Skin Corrosion/Irritation: Not classified as skin irritant under GHS
Serious Eye Damage/Irritation: Mild, reversible irritation in animal studies
Respiratory/Skin Sensitization: Not a known sensitizer
Repeated Dose Toxicity: No significant organ toxicity in studies
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity: Negative results in standard genotoxicity tests
Reproductive Toxicity: No evidence of reproductive toxicity in available data
Other Information: Subject to limited gastrointestinal absorption; generally well-tolerated in topical use, based on safety data in cosmetic applications
Ecotoxicity: Low aquatic toxicity, LC50 (fish, 96 hr): >1,000 mg/L
Persistence and Degradability: Readily biodegradable, undergoes rapid mineralization in wastewater treatment
Bioaccumulative Potential: Low potential for bioaccumulation (BCF <10)
Mobility in Soil: High mobility, expected to distribute in water phase
Other Adverse Effects: No significant impact on the environment under normal disposal or use
Waste Treatment Methods: Incineration or disposal through licensed chemical waste contractor
Product Disposal: Do not discharge undiluted into sewage or waterways
Contaminated Packaging: Wash and recycle containers if possible, otherwise dispose of as chemical waste
Additional advice: Follow local regulations regarding chemical disposal, never pour large quantities down drain
UN Number: Not regulated as dangerous goods
Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: No special transport precautions needed; ship in tightly closed containers, protect from excessive heat
Inventory Listings: Registered under TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia), other national inventories
TSCA Status: Listed
OSHA Hazards: Not hazardous
SARA Title III: Not listed under Sections 302, 304, 313
WHMIS Classification (Canada): Not controlled
REACH Status (EU): Registered for use in cosmetics and personal care
Other Regulations: Not restricted for cosmetic use by EU Cosmetics Regulation or US FDA
