Histry Chem

Conhecimento

Material Safety Data Sheet (MSDS): Dimethyl Adipate (DMA)

Identification

Product Name: Dimethyl Adipate
Chemical Formula: C8H14O4
Synonyms: Adipic acid dimethyl ester, DMA
CAS Number: 627-93-0
Use: Intermediate for chemical synthesis, solvent for industrial applications, plasticizer
Manufacturer Contact: Phone, address, and emergency contact listed on the original supplier label.

Hazard Identification

GHS Classification: Eye Irritation Category 2A, Skin Irritation Category 3
Hazard Statements: Causes serious eye irritation, mild skin irritation possible
Signal Word: Warning
Pictograms: Exclamation mark symbol
Precautionary Statements: Wear protective gloves/eye protection, avoid breathing vapors, wash hands after handling, use only outdoors or in well-ventilated areas
Potential Health Effects: Eye irritation, mild skin irritation, respiratory discomfort from mist or vapor inhalation; ingestion may cause gastrointestinal upset
Target Organs: Eyes, skin, respiratory system

Composition / Information on Ingredients

Chemical: Dimethyl Adipate
Concentration: >99%
Additives/Impurities: Trace impurities only (confirmed per batch test reports)

First Aid Measures

Inhalation: Move person to fresh air, keep comfortable, seek medical attention for symptoms
Skin Contact: Remove contaminated clothing, wash skin thoroughly with water and soap, get medical help if irritation develops
Eye Contact: Rinse eyes carefully with water for several minutes, remove contact lenses if present, continue rinsing, seek medical attention for persistent irritation
Ingestion: Rinse mouth with water if conscious, do not induce vomiting, seek immediate medical assistance
Important Symptoms/Effects: Redness, irritation, discomfort in eyes, possible mild skin irritation, respiratory irritation
Medical Attention: Doctors should provide symptomatic treatment

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Do not use direct water stream, which can spread fire
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, possible acrid smoke
Specific Hazards: Drum rupture from heat, vapors may form explosive mixtures with air
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear, avoid inhaling vapors and smoke
Fire Fighting Instructions: Use water spray to cool containers, keep away from runoff

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate spill area, use appropriate PPE including gloves, goggles, chemical-resistant clothing
Environmental Precautions: Prevent entry into sewers, waterways, and soil
Spill Cleanup: Absorb with inert material (sand, vermiculite), transfer to suitable containers for disposal, wash area with detergent and water, collect waste for proper treatment
Methods for Cleaning Up: Manual using non-sparking tools, avoid creating dust or mist, do not flush to drain

Handling and Storage

Precautions for Safe Handling: Maintain local exhaust ventilation, avoid contact with skin and eyes, keep containers tightly closed, do not inhale vapors, wash hands and face after handling
Safe Storage Conditions: Store in tightly sealed original containers, cool dry area, away from direct sunlight, heat sources, and incompatible substances (strong oxidizers, acids, bases)
Incompatibilities: Oxidizing agents, strong acids
Storage Temperature: Preferably 2-8°C for best shelf life stability
Other Information: Containers should be labeled and checked for leaks regularly

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA or ACGIH limits, control to minimize exposure
Engineering Controls: Use local exhaust ventilation, eye wash stations, safety showers nearby
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, long-sleeved clothing
Respiratory Protection: Use NIOSH-approved respirator for high vapor amounts or during spill cleanup
Hygiene Measures: Remove contaminated clothing, wash thoroughly before breaks and after shift
Environmental Exposure Controls: Prevent discharge to environment, manage spill procedures responsibly

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Faint ester-like odor
pH: Not applicable (non-aqueous)
Melting Point: -16°C
Boiling Point: 232°C
Flash Point: 118°C (closed cup)
Evaporation Rate: Very slow
Flammability: Combustible at elevated temperatures
Vapor Pressure: 0.03 mmHg at 20°C
Vapor Density: 5.7 (air=1)
Relative Density: 1.062 g/cm³ at 20°C
Solubility: Moderately soluble in water, high solubility in organic solvents
Partition Coefficient (Log Kow): About 1.2
Viscosity: Low
Auto-ignition Temperature: 425°C

Stability and Reactivity

Chemical Stability: Stable under standard conditions (provided dry, inert atmosphere and cool storage)
Possibility of Hazardous Reactions: None under recommended storage and handling
Conditions to Avoid: High temperatures, open flames, strong oxidizers
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other unknown toxins on thermal decomposition

Toxicological Information

Acute Toxicity: Low oral toxicity (rat LD50 ~5000 mg/kg), low dermal toxicity
Skin Corrosion/Irritation: Mild irritant
Serious Eye Damage/Irritation: Causes strong eye irritation, reversible
Respiratory Sensitization: Not expected
Germ Cell Mutagenicity: No evidence in available studies
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: No evidence of reproductive or developmental effects
Target Organ Effects: Eyes, skin, respiratory tract irritation
Signs/Symptoms of Exposure: Eye redness, watering, stinging; mild skin discomfort; throat irritation at high vapor concentration

Ecological Information

Ecotoxicity: Expected to be low toxicity to aquatic life (LC50 fish >100 mg/L)
Persistence and Degradability: Biodegradable in soil and water
Bioaccumulative Potential: Low (Log Kow near zero)
Mobility in Soil: Moderate mobility, may leach to groundwater if released in large quantities
Other Adverse Effects: Follow good chemical management practices to prevent ecosystem impact

Disposal Considerations

Waste Treatment Methods: Dispose by incineration in approved facility, comply with local/state/national regulations
Contaminated Packaging: Triple rinse containers before recycling or disposal, label appropriately
Do Not: Pour product into drains, waterways, open soil
Special Precautions: Check local regulations, consult hazardous waste professional as needed

Transport Information

UN Number: Not regulated for ground, air, or sea transport in most regions
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Transport Precautions: Secure tightly, avoid direct sun and overheating during transit, follow internal SOPs for shipping chemicals

Regulatory Information

US TSCA: Listed
EU REACH: Registered
GHS Label Elements: Warning, hazard and precautionary statements specified above
SARA Title III Sections 311/312: Not classified as immediate or delayed health hazard
SARA Title III Sections 313: DMA not present in quantities triggering reporting
Canada DSL/NDSL: Listed
Other Regulations: Subject to state/local restrictions in some areas, always verify current compliance status before use/import/export