Product Name: Diisopropyl Adipate
Chemical Formula: C12H22O4
Synonyms: Hexanedioic acid, diisopropyl ester; Adipic acid, diisopropyl ester
CAS Number: 6938-94-9
Recommended Use: Solvent, emollient in cosmetics, plasticizer for polymers
Supplier Information: Manufacturer’s address, emergency contact phone numbers available on label and shipping documents
Emergency Contact: Local poison center, company emergency response line
GHS Classification: Not classified as hazardous according to GHS
Signal Word: None
Hazard Statements: Generally considered low hazard but can cause eye and skin irritation
Hazard Symbols: None required under GHS
Precautionary Statements: Avoid contact with eyes, prolonged skin exposure, ingestion
Acute Effects: Mild irritation if inhaled, swallowed, or splashed into eyes
Chronic Effects: No long-term health effects have been documented in available studies
Chemical Identity: Diisopropyl Adipate
Common Name: DIPA
CAS No.: 6938-94-9
Concentration: 98–100%
Impurities: Trace amount of related esters and unreacted precursors
Inhalation: Move affected person to fresh air, assist breathing if needed, seek medical attention for continued discomfort
Eye Contact: Rinse with gentle stream of water for at least 15 minutes, remove contact lenses if present, consult a physician if symptoms persist
Skin Contact: Wash area with soap and water, remove contaminated clothing, get advice from doctor if irritation or rash develops
Ingestion: Rinse mouth, give water if person is conscious, avoid inducing vomiting, seek medical attention immediately for symptoms or large amount
Notes for Physicians: Treat symptomatically, no specific antidote known
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: Do not use direct water jet
Specific Hazards Arising From Fire: Vapors may form explosive mixtures with air, burning may produce carbon monoxide, carbon dioxide, irritating fumes
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Firefighting Procedures: Move containers from area if safe, cool fire-exposed containers with water, prevent runoff from entering drains or waterways
Personal Precautions: Use suitable personal protective equipment, ventilate area, avoid inhalation of vapors and contact with skin or eyes
Environmental Precautions: Prevent entry into sewers, drains, or waterways, contain spillage with absorbent material
Spillage Response: Stop leak if possible without risk, absorb with earth, sand, or suitable non-combustible material; store in labeled containers for disposal
Large Spill Response: Evacuate area, consult local authorities for advice and containment
Safe Handling: Handle in well-ventilated area, avoid inhalation of aerosol and vapor, avoid contact with skin and eyes, wash hands after handling
Storage Conditions: Store in original tightly closed container, in cool, dry, well-ventilated area away from sources of ignition or intense heat
Incompatible Materials: Strong oxidizers, acids or alkalis may cause decomposition or reaction
Other Precautions: Keep out of reach of children, avoid smoking, eating, drinking in storage and handling areas
Exposure Limits: No occupational exposure limits established for DIPA
Engineering Controls: Use local exhaust ventilation to control exposure, provide emergency eye wash stations and showers where risk exists
Personal Protective Equipment: Chemical-resistant gloves, splash-proof goggles, lab coat or apron
Respiratory Protection: Use approved respirator if exposure limits are likely to be exceeded, especially for mist or vapor
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing and wash before reuse
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild ester-like
Odor Threshold: Not available
pH: Not applicable (non-aqueous)
Melting Point / Freezing Point: -35°C
Boiling Point / Range: 151–153°C at 15 mm Hg
Flash Point: 134°C (closed cup)
Evaporation Rate: Not determined
Flammability: Not readily flammable, can burn under fire conditions
Upper/Lower Flammability Limits: Not established
Vapor Pressure: 0.05 mm Hg at 25°C
Vapor Density: > 1 (air = 1)
Relative Density: 0.97 g/cm³ at 20°C
Solubility: Slightly soluble in water, miscible with organic solvents
Partition Coefficient (n-octanol/water): 3.6
Auto-ignition Temperature: Not established
Decomposition Temperature: Not available
Viscosity: 11.8 mm²/s at 20°C
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No hazardous reactivity under normal conditions
Conditions to Avoid: Excessive heat, open flames, strong oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, small amounts of other organic compounds
Polymerization: Product does not undergo hazardous polymerization
Acute Toxicity: Low toxicity by oral and dermal route, based on animal study data; LD50 (oral, rat) > 5000 mg/kg
Skin Corrosion/Irritation: May cause mild, reversible irritation
Eye Damage/Irritation: Can cause temporary irritation
Respiratory Sensitization: Not reported
Skin Sensitization: Not reported
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity: Not expected to present mutagenic hazards
Reproductive Toxicity: No data available indicating adverse reproductive effects
Target Organ Effects: No target organ toxicity documented in available literature
Aquatic Toxicity: Low acute toxicity to fish, daphnia, and algae; estimated LC50 (Fish, 96h) > 100 mg/L
Mobility in Soil: Moderate, based on partition coefficient and solubility
Persistence and Degradability: Expected to be biodegradable in the environment based on structure-activity relationship
Bioaccumulative Potential: Moderate potential, due to moderate log Kow
Other Adverse Effects: No evidence for significant long-term environmental impact in typical use scenarios
Product Disposal: Dispose of material in accordance with federal, state, and local regulations; do not release into sewers, surface waters, or soil
Contaminated Packaging: Containers to be treated as hazardous waste; rinse well, follow local disposal regulations
Recommended Disposal Methods: Use authorized chemical waste contractor; incineration preferred for large quantities
Waste Codes: Check applicable local, regional, national regulations for waste classification
UN Number: Not regulated for transport
UN Proper Shipping Name: Diisopropyl Adipate
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions for User: No particular requirements under normal conditions of transport, ensure closure integrity to prevent leaks
International Regulations: Listed under chemical inventories such as TSCA (USA), EINECS (Europe), DSL (Canada)
USA: Not subject to reporting requirements under SARA Title III, not on CERCLA hazardous substances list
EU: Not classified as dangerous under Regulation (EC) No 1272/2008 (CLP/GHS)
Canada: Listed on Domestic Substances List, not controlled under WHMIS
Australia: Listed on AICS
Other: Check current country-specific regulations for restrictions or labeling requirements
Labeling: Ensure container and workplace labeling comply with local laws and best practice
