Histry Chem

Conhecimento

Material Safety Data Sheet: Diethyl Adipate (DEA)

1. Identification

Substance Name: Diethyl Adipate
Chemical Formula: C10H18O4
SYNONYMS: DEA, Diethyl hexanedioate
CAS Number: 141-28-6
EC Number: 205-480-7
Intended Use: Industrial solvent, plasticizer, intermediate in organic synthesis
Manufacturer/Supplier: [Supplier’s Name]
Emergency Contact: [Emergency Phone Number]

2. Hazard Identification

GHS Classification: Skin irritation (Category 3), Eye irritation (Category 2B)
Signal Word: Warning
Hazard Statements: May cause mild skin and eye irritation, Inhalation or ingestion can lead to dizziness or gastrointestinal discomfort
Pictograms: Exclamation mark
Precautionary Statements: Avoid inhaling vapors, wash hands after use, wear protective equipment
Hazard Routes: Inhalation, skin and eye contact, ingestion

3. Composition / Information on Ingredients

Chemical Identity: Diethyl Adipate
PURITY (%): ≥99
Impurities: May contain minor traces of related adipate esters
CAS Number: 141-28-6
Proportion: Main ingredient, may include residual solvents below 1%

4. First Aid Measures

Inhalation: Move person to fresh air, keep at rest, consult medical attention if symptoms persist
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing
Eye Contact: Flush carefully with water for at least 15 minutes, seek medical help if irritation develops
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical assistance
Symptoms: May involve mild skin or eye irritation, headache, nausea if inhaled or swallowed
Advice for Doctor: Treat symptomatically

5. Fire-Fighting Measures

Suitable Extinguishing Media: Use CO2, dry powder, foam, or water spray to fight fire
Unsuitable Media: Do not use water jet directly on burning liquid
Hazards: Vapors can form explosive mixtures with air, may emit toxic fumes such as carbon oxides on combustion
Protective Equipment: Wear self-contained breathing apparatus and suitable protective clothing
Special Procedures: Remove containers from fire if safe, cool closed containers with water mist

6. Accidental Release Measures

Personal Protection: Wear gloves, goggles, suitable protective clothing, do not breathe vapors
Environmental Precautions: Prevent material entering drains or water courses
Cleanup Methods: Absorb spill with sand, earth, or commercial absorbent, collect in a suitable container for disposal
Ventilation: Provide adequate ventilation during and after clean up
Disposal: Refer to disposal considerations for safe discarding

7. Handling and Storage

Handling: Avoid skin and eye contact, avoid inhalation of vapors or mists, use local exhaust ventilation
Storage Conditions: Store in tightly closed containers, keep in cool, dry, well-ventilated area away from heat or ignition sources
Incompatibilities: Keep away from oxidizers, acids, bases
Storage Temperature: Preferably below 25°C, protect from direct sunlight and moisture
Container Materials: Use corrosion-resistant containers

8. Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA or ACGIH limit, recommend minimizing exposure
Engineering Controls: Use local exhaust ventilation, eye wash stations, safety showers
Respiratory Protection: Use NIOSH-approved respirators if vapor concentrations are high
Hand Protection: Wear chemical-resistant gloves (nitrile, rubber)
Eye Protection: Chemical safety goggles or splash-proof visor
Skin Protection: Overalls, lab coats, avoid direct skin contact
Hygiene Controls: Wash hands before breaks and after handling, remove contaminated clothing

9. Physical and Chemical Properties

Physical State: Liquid
Appearance: Clear, colorless to pale yellow
Odor: Slight, ester-like
Melting Point: -32°C
Boiling Point: 214-216°C
Flash Point: 104°C (closed cup)
Auto-ignition Temperature: 400°C
Vapor Pressure: 0.05 mmHg at 25°C
Density: 1.01–1.02 g/cm³ at 20°C
Solubility: Slightly soluble in water, miscible with most organic solvents
Viscosity: Low
Partition Coefficient (log Pow): 2.8–3.2

10. Stability and Reactivity

Chemical Stability: Stable under normal temperature and pressure
Decomposition: May release carbon monoxide, carbon dioxide on combustion
Reactivity: Can react with strong oxidizers, acids, or bases
Hazardous Polymerization: Does not occur
Conditions to Avoid: Excessive heat, open flames, incompatible materials
Incompatible Materials: Strong acids, oxidizing agents, reducing agents

11. Toxicological Information

Acute Toxicity: Oral LD50 (rat): >8,000 mg/kg
Inhalation Toxicity: No data for acute effects, may cause nausea or dizziness in high vapor concentrations
Skin Corrosion/Irritation: Slight irritant
Eye Damage/Irritation: Mild transient irritation
Skin Sensitization: Not a skin sensitizer
Chronic Toxicity: No evidence of mutagenicity, carcinogenicity, teratogenicity based on available data
Other Effects: May cause gastrointestinal upset if ingested

12. Ecological Information

Ecotoxicity: Moderately toxic to aquatic organisms, LC50 (fish, 96h): 56 mg/L
Persistence and Degradability: Biodegradable, expected to degrade in environment
Bioaccumulative Potential: Low to moderate, based on log Pow values
Mobility in Soil: Moderate, can leach to groundwater in liquid form
Other Adverse Effects: Avoid release into waterways to prevent local ecological harm

13. Disposal Considerations

Waste Disposal Methods: Dispose as hazardous chemical waste according to local regulations
Container Disposal: Empty containers should be triple-rinsed before discarding or recycling
Disposal Precautions: Do not pour into drains or environment, incinerate under controlled conditions where permitted
Regulatory Waste Codes: Check applicable RCRA codes for specific classification

14. Transport Information

UN Number: Not regulated under UN transport
Proper Shipping Name: Diethyl Adipate
Transport Hazard Class: Not classified as dangerous for transport
Packing Group: Not assigned
Marine Pollutant: No
Special Transport Precautions: Secure containers, prevent leaks, transport in compliance with local and international rules

15. Regulatory Information

OSHA Status: Not classified as hazardous under OSHA
TSCA Status: Listed in US TSCA inventory
REACH Registration: Complies with EU REACH standards
SARA Title III: Not subject to Section 302, 304, or 313
WHMIS: Classified as D2B – skin/eye irritant
California Proposition 65: Not listed
Labels Required: GHS compliant labeling
Other Regulations: Adhere to all applicable safety, health, and environmental regulations across regions where used or sold