Chemical Name: Adipic Acid
Synonyms: Hexanedioic acid
Chemical Formula: C6H10O4
CAS Number: 124-04-9
Recommended Use: Intermediate for nylon production, plasticizer, polyurethane, food additive, adhesives
Supplier: Contact manufacturer for specific contact details and emergency phone numbers
Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific Target Organ Toxicity - Single Exposure (Category 3)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, causes skin irritation, may cause respiratory irritation
Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Wash hands thoroughly after handling, avoid breathing dust, wear protective gloves and eye protection, use only outdoors or in a well-ventilated area
Substance: Pure Adipic Acid
Content: 99 – 100%
Impurities: Trace amounts of water and organic byproducts possible, specific breakdown available from manufacturer
Inhalation: Move to fresh air immediately, seek medical attention if breathing becomes difficult, provide oxygen if needed
Skin Contact: Remove contaminated clothing, wash affected area thoroughly with soap and water, consult a doctor if irritation persists
Eye Contact: Rinse with water for 15 minutes keeping eyelids open, remove contact lenses if present, get medical help promptly
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention, never give anything by mouth to an unconscious person
Acute/Delayed Symptoms: May include irritation, redness, coughing, sore throat, abdominal discomfort
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Specific Hazards: Emits toxic fumes of carbon oxides under fire conditions, dust may form explosive mixtures with air
Special Protective Equipment: Firefighters need full protective clothing and self-contained breathing apparatus
Advice for Firefighters: Fight fire from a safe distance, prevent runoff from entering drains, cool containers with water spray to prevent rupture
Personal Precautions: Ventilate area, avoid dust formation, wear appropriate personal protective equipment including gloves, goggles, and mask
Environmental Precautions: Prevent further leakage or spillage if safe, avoid discharge into drains, water courses, or onto ground
Methods for Cleaning Up: Pick up and arrange disposal without creating dust, sweep or vacuum up material using equipment fitted with HEPA filters, place in suitable container for disposal
Emergency Procedures: Isolate hazard area, keep unnecessary personnel away
Handling: Use only in well-ventilated areas, minimize dust generation and accumulation, avoid breathing dust, avoid contact with skin, eyes, and clothing, practice good industrial hygiene
Storage: Store in closed, labeled containers in a cool, dry, well-ventilated place away from incompatible substances such as strong oxidizing agents and bases, prevent moisture contact, keep out of reach of children
Packaging Materials: Use containers made from corrosion-resistant materials, inspect regularly for integrity
Occupational Exposure Limits: No OSHA PEL, ACGIH TLV: 5 mg/m³ (inhalable fraction for particulates not otherwise classified)
Engineering Controls: Provide adequate ventilation, local exhaust preferred, use enclosed processes
Personal Protective Equipment: Safety glasses with side shields or chemical goggles, gloves made of resistant material (PVC, nitrile), lab coat or coveralls, dust mask or respirator if airborne dust exceeds limit
Hygiene Measures: Wash hands, forearms, and face after handling, remove contaminated clothing, do not eat, drink, or smoke during use
Appearance: White crystalline powder
Odor: Slightly pungent
Melting Point: 151–154 °C
Boiling Point: 337.5 °C
Vapor Pressure: 1 mm Hg at 218 °C
Solubility: Soluble in water, soluble in alcohol and acetone
pH (aqueous): Around 2.9 (0.1 M solution)
Density: 1.36 g/cm³ at 20 °C
Flash Point: 210 °C (closed cup)
Auto-ignition Temperature: 405 °C
Partition Coefficient (log Pow): 0.093
Evaporation Rate: Negligible
Chemical Stability: Stable under recommended storage conditions
Incompatibility: Strong oxidizing agents, reducing agents, bases
Hazardous Decomposition: Carbon monoxide, carbon dioxide, acrid smoke and fumes
Polymerization: Will not occur under normal handling
Conditions to Avoid: Excessive heat, sparks, open flames, moisture, contact with incompatible substances
Routes of Exposure: Inhalation, ingestion, skin, eyes
Acute Toxicity: LD50 oral (rat): 5560 mg/kg
Skin Corrosion/Irritation: May cause moderate irritation
Serious Eye Damage/Irritation: Severe irritation possible
Respiratory Sensitization: Not classified
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: Not expected to be a reproductive hazard
Chronic Effects: Repeated exposure may cause respiratory tract irritation, skin dryness or cracking
Ecotoxicity: Adipic acid has low toxicity to aquatic organisms, LC50 (fish, 96 hr): 97 mg/L (Lepomis macrochirus), EC50 (Daphnia, 48 hr): 85.7 mg/L
Persistence and Degradability: Readily biodegradable under aerobic conditions
Bioaccumulation: Low potential, log Kow 0.08–0.13
Mobility in Soil: High mobility, significant leaching potential
Other Adverse Effects: No known significant effects or critical hazards under normal use and handling
Disposal Methods: Dispose of in accordance with local, regional, and national regulations for hazardous waste, incineration in a chemical incinerator with afterburner and scrubber recommended
Contaminated Packaging: Empty containers should be decontaminated and disposed of as hazardous waste, follow all local requirements for packaging disposal
Precautions: Avoid disposal in drains, water courses, or landfills unsuitable for hazardous chemicals, consult a licensed waste contractor
UN Number: 9077
Proper Shipping Name: Adipic Acid
Transport Hazard Class: Non-regulated for land (DOT), sea (IMDG), air (IATA)
Packing Group: Not classified
Environmental Hazards: Not considered marine pollutant, not hazardous under transport, accidental spillage may cause local environmental harm
Special Precautions for User: Avoid formation of dust clouds, keep container tightly closed and dry, follow all safety protocols during transit
OSHA Status: Considered hazardous based on GHS classification
TSCA: Listed on the U.S. TSCA inventory
SARA 302/304: Not listed
SARA 313: Not listed
California Prop 65: Not listed as a carcinogen or reproductive toxin
REACH Regulation (EC): Registered and supported by full safety dossier, uses and risks assessed
Other International Inventories: Listed on AICS (Australia), DSL/NDSL (Canada), ECL (Korea), ENCS (Japan), NZIoC (New Zealand), PICCS (Philippines), IECSC (China)
Labelling: Proper GHS labelling, hazard and precautionary statements supplied by distributor or reseller
