Product Name: 3'-Hydroxyacetophenone
Chemical Name: 1-(3-Hydroxyphenyl)ethanone
CAS Number: 121-71-1
Synonyms: m-Hydroxyacetophenone, 3-HAP
Molecular Formula: C8H8O2
Molecular Weight: 136.15 g/mol
Recommended Use: Research and development, flavoring agent, fragrance intermediate
Manufacturer/Supplier Details: Chemical laboratory supplier or manufacturer; address and contact provided on company website
Emergency Contact Number: Refer to local jurisdictional emergency numbers or supplier-specific emergency helpline
GHS Classification: Not classified as dangerous according to current regulations; minor irritancy possible
Label Elements: No pictogram required; precautionary language advised
Signal Word: None
Hazard Statements: Can cause mild irritation to skin, eyes, or respiratory tract with prolonged exposure
Precautionary Statements: Avoid contact with eyes and skin, do not inhale dust, handle with adequate ventilation
Health Hazards: May cause irritation upon contact; repeated exposure might lead to dermatitis or respiratory discomfort
Environmental Hazards: Negligible in small quantities, caution in large-scale spillage due to possible waterway contamination
Physical Hazards: Not classified as flammable or explosive, dust may be slightly combustible
Chemical Identity: 3'-Hydroxyacetophenone
Concentration: >99% pure in analytical samples; may contain minor synthesis residuals
Impurities/Additives: Most preparations contain less than 1% total impurities, generally unclassified
Chemical Family: Aromatic ketones
Inhalation: Move exposed person to fresh air, keep comfortable for breathing, consult a doctor if symptoms persist
Skin Contact: Wash affected area thoroughly with soap and water, remove contaminated clothing
Eye Contact: Flush eyes continuously with clean water for at least 15 minutes, seek medical attention if irritation remains
Ingestion: Rinse mouth with water, do not induce vomiting, contact physician if feeling unwell or for advice
Acute Effects: Irritation, soreness, mild discomfort
Delayed Effects: Potential dermatitis or respiratory issues after repeated contact or prolonged exposure
Extinguishing Media: Use dry chemical, foam, CO2, or water spray
Unsuitable Media: Direct water jets could spread powdered product
Special Hazards from Combustion: Carbon monoxide, carbon dioxide, and potentially irritating fumes
Protective Equipment: Wear self-contained breathing apparatus and full firefighting gear
Advice for Firefighters: Keep fire-exposed containers cool with water spray, collect runoff to prevent environmental contamination
Personal Precautions: Avoid dust formation, wear protective equipment including gloves, goggles, and mask
Environmental Precautions: Prevent product from entering drains, sewers, soil, and surface waters in bulk
Containment: Sweep up material carefully, avoiding raising dust, transfer to a labeled, closed container for disposal
Cleanup Methods: Ventilate area, wash surfaces with plenty of water after cleanup, dispose of according to regulatory guidelines
Handling: Operate in well-ventilated spaces, avoid contact with eyes and skin, wash hands after handling
Storage: Store in tightly closed container, away from direct sunlight, cool dry place, segregate from strong oxidizers
Incompatibilities: Strong bases and oxidizing agents
Specific Precautions: Avoid generating airborne dust during handling or transfers
Occupational Exposure Limits: No established OSHA/ACGIH limits
Engineering Controls: Chemical fume hood, proper ventilation for bulk handling
Personal Protective Equipment: Safety glasses with side shields, chemical-resistant gloves, lab coat
Respiratory Protection: Dust mask or respirator if dust is generated above nuisance levels
Hygiene Measures: Keep away from food and drink, clean hands thoroughly before meals or after work
Appearance: Crystalline white to pale yellow solid
Odor: Faint, aromatic odor
pH: Not available (insoluble in water, solution pH not defined)
Melting Point: 108–110 °C
Boiling Point: Decomposes before boiling at atmospheric pressure
Flash Point: 175 °C (closed cup, approximate)
Flammability: Not classified as highly flammable
Vapor Pressure: Negligible under ambient conditions
Solubility: Sparingly soluble in water; soluble in ethanol, DMSO, acetone
Partition Coefficient (log Kow): Approximate value 1.4–2.0
Density: 1.163 g/cm³
Evaporation Rate: Not determined
Chemical Stability: Product remains stable under normal temperatures and recommended storage practices
Conditions to Avoid: Prolonged exposure to light, high temperatures, moisture
Incompatible Materials: Strong oxidizers, bases, acids
Hazardous Decomposition: Burning can generate CO, CO2, phenolic fumes
Polymerization: No hazardous polymerization anticipated
Acute Toxicity: Oral LD50 (rat) >500 mg/kg, considered low toxicity
Skin and Eye Irritation: May cause mild irritation, redness, discomfort
Carcinogenicity: No evidence of carcinogenic effects in available data
Mutagenicity: Data limited; not identified as mutagenic
Repeated Dose Toxicity: Prolonged exposure may cause dermatitis or respiratory irritation
Symptoms of Overexposure: Itchy skin, sore eyes, dry throat
Routes of Exposure: Ingestion, inhalation, dermal contact
Ecotoxicity: No acute aquatic toxicity observed at low concentrations, data remains limited
Mobility: Expected to have moderate mobility in soil, depends on soil type and conditions
Persistence and Degradability: Partial biodegradation anticipated, product not readily biodegradable in all environments
Bioaccumulation Potential: Low log Kow indicates minor bioaccumulation risk
Aquatic Environmental Impact: Avoid significant discharges to water bodies; follow regulatory disposal guidelines
Waste Disposal Methods: Dispose of contents and containers in accordance with local, state, and federal regulations
Unused Product: Recommend chemical incineration or disposal through licensed professional waste disposal contractor
Contaminated Packaging: Wash before reuse or dispose as hazardous chemical waste
Disposal Precautions: Do not pour down drains, avoid release to the environment, keep material out of groundwater and surface water
UN Number: Not regulated
Proper Shipping Name: 3'-Hydroxyacetophenone, not classified as dangerous for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not designated
Special Transport Precautions: Keep container tightly closed, upright, away from foodstuffs and combustibles during transport
TSCA Status: Listed
DSL/NDSL (Canada): Listed
EU REACH Status: Registered or pre-registered
SARA Title III: Not classified as hazardous
California Proposition 65: Not listed
Other Regulations: OSHA hazard communication standard applies, always refer to local legislation for additional compliance requirements
