Chemical Name: 1,8-Octanediol
Synonyms: Octamethylene glycol, Octane-1,8-diol
CAS Number: 629-41-4
Molecular Formula: C8H18O2
Molecular Weight: 146.23 g/mol
Recommended Use: Intermediate for chemical synthesis, polymer manufacture, cosmetics, personal care formulations
Supplier Information: Refer to packaging or invoice for supplier contact details
Emergency Phone: Refer to local guidelines and supplier label for emergency contact numbers
GHS Classification: Not classified as hazardous according to GHS criteria
Label Elements: No pictogram required. No signal word required.
Hazard Statements: May cause mild irritation to eyes and skin on prolonged or repeated contact
Precautionary Statements: Avoid prolonged skin and eye contact; wash hands thoroughly after handling
Other Hazards: Spilled material can create slip hazard; not combustible but may support combustion in presence of strong oxidizers
Ingredient: 1,8-Octanediol
Concentration: ≥99% (pure substance)
Impurities: Typical byproducts of synthesis may include traces of water and related diols; not expected to affect classification
Inhalation: Move to fresh air if large volumes cause discomfort; seek medical attention if symptoms persist
Skin Contact: Wash generously with soap and water; remove contaminated clothing and launder before reuse; seek medical advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; get medical attention if irritation persists
Ingestion: Rinse mouth with water; do not induce vomiting; seek medical attention in case of discomfort or accidental large quantity ingestion
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam
Unsuitable Extinguishing Media: Strong water jets may spread material
Specific Hazards: Combustion may produce carbon oxides and other irritant fumes
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective suit
Special Precautions: Approach fire from upwind to avoid hazardous vapors and decomposition products; keep containers cool by spraying with water if exposed to fire
Personal Precautions: Evacuate unnecessary personnel; wear suitable protective equipment including gloves and goggles
Environmental Precautions: Prevent product from entering drains, waterways, or soil
Methods for Containment: Stop leak if safe to do so; dike with inert absorbent material (sand, earth)
Clean-up Methods: Absorb residue with sand or other non-combustible absorbent; shovel into labeled waste containers for proper disposal
Handling: Use in well-ventilated area; avoid contact with skin and eyes; wear appropriate personal protective equipment
Storage Conditions: Store in tightly closed containers at room temperature in a cool, dry, well-ventilated area away from heat, direct sunlight, and incompatible substances such as strong oxidizers
Incompatible Materials: Keep away from strong acids, strong bases, and oxidizing agents
General Hygiene: Wash hands after handling; avoid eating, drinking, or smoking in work area
Occupational Exposure Limits: No specific occupational exposure limits established
Engineering Controls: Adequate mechanical ventilation, eyewash stations, and safety showers in work area
Personal Protective Equipment: Safety glasses with side shields, chemical-resistant gloves (nitrile or similar), lab coat
Respiratory Protection: Not usually required in well-ventilated setting; use appropriate mask if dust or aerosol generated
Environmental Controls: Avoid release to the environment; follow local regulatory requirements for exhaust and wastewater treatment
Appearance: White crystalline solid
Odor: Faint, characteristic
pH (1% solution): Approx. 6-7
Melting Point: 60-62°C
Boiling Point: 255-257°C (at 1 atm)
Flash Point: 131°C (closed cup)
Solubility: Soluble in water, ethanol, diethyl ether
Vapor Pressure: Negligible at 20°C
Relative Density: 0.96 g/cm³ at 20°C
Partition Coefficient (log Kow): Approx. 0.2
Viscosity: Low (liquid melts near room temp)
Chemical Stability: Stable under normal storage and handling conditions
Hazardous Reactions: None known under normal conditions; may react with strong oxidizers
Decomposition Products: Thermal decomposition can produce carbon monoxide, carbon dioxide, and other irritating fumes
Conditions to Avoid: Excessive heat, open flames, and direct sunlight
Acute Toxicity: Low toxicity; oral LD50 (rat) >1000 mg/kg
Skin Corrosion/Irritation: Mild irritant after prolonged or repeated contact
Serious Eye Damage/Irritation: May cause mild, reversible irritation
Respiratory Sensitization: No data indicate sensitization
Germ Cell Mutagenicity: Not mutagenic based on available information
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of reproductive toxicity in animal studies
Target Organ Effects: No known organ toxicity from expected exposure
Ecotoxicity: Low acute toxicity to aquatic organisms; LC50 (fish) >100 mg/L (OECD 203)
Persistence and Degradability: Readily biodegradable in the environment
Bioaccumulative Potential: Bioaccumulation unlikely due to low log Kow
Mobility in Soil: High solubility in water; expected to have high mobility in soil
Results of PBT and vPvB Assessment: Does not meet PBT or vPvB criteria according to current regulations
Waste Disposal Methods: Dispose of contents/containers in accordance with local, regional, and national regulations; chemical incineration in controlled facility recommended
Contaminated Packaging: Rinse container and recycle or dispose of as hazardous waste, following local requirements
Avoid: Discharge to waterways, drains, or environment without proper treatment
UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Special Precautions: Keep container tightly closed and upright during transport; protect from physical damage
US TSCA Inventory: Listed
EU REACH Status: Registered
Canada DSL/NDSL: Listed
Australia AICS: Listed
Japan ENCS: Listed
China IECSC: Listed
Regulatory Restrictions: Comply with chemical safety, environmental, and occupational health regulations for industrial and consumer uses; country-specific information may apply
