Product Name: 1,8-Dichlorooctane
Chemical Formula: C8H16Cl2
CAS Number: 2162-98-3
Synonyms: Octamethylene dichloride, 1,8-Octylene dichloride
Recommended Use: Used in organic synthesis, laboratory research, specialty chemicals
Manufacturer: Please refer to supplier’s details on packaging
Contact Information: Refer to supplied documentation for emergency numbers and manufacturer address
GHS Classification: Skin Irritation Category 2, Eye Irritation Category 2A, Acute Toxicity (Oral) Category 4, Acute Toxicity (Inhalation) Category 4
Hazard Symbols: Exclamation mark, Health hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed or inhaled. Causes skin and eye irritation. May cause respiratory irritation.
Precautionary Statements: Avoid breathing dust, fumes, gas, mist, vapors, and spray. Wash exposed skin thoroughly after handling. Use only outdoors or in well-ventilated areas. Wear protective gloves, eye protection, face protection, and suitable clothing.
Chemical Name: 1,8-Dichlorooctane
Concentration: 98%–100%
Impurities: Trace organic impurities below 2% (often from manufacturing) can vary. None known with significant effect on hazard profile in standard samples.
Inhalation: Move the affected person to fresh air and keep at rest in a position comfortable for breathing. Give oxygen if breathing is difficult; seek immediate medical attention if symptoms persist, such as dizziness, headache, nausea, or respiratory irritation.
Skin Contact: Remove contaminated clothing and wash the skin gently with soap and copious amounts of water for at least 15 minutes. Get medical attention for persistent irritation, burning, or rash.
Eye Contact: Rinse carefully with running water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Remove any contact lenses if present and easy to do. Seek medical help if irritation continues.
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel. If the person feels unwell, get medical advice immediately. Never give anything by mouth to someone who is unconscious or convulsing.
Most Important Symptoms & Effects: Burning sensation, coughing, shortness of breath, redness, pain, or eye-watering may arise after exposure.
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Do not use straight water jets on product fires.
Specific Hazards: Releases toxic vapors under fire conditions such as hydrogen chloride, carbon oxides, and phosgene.
Protection for Firefighters: Wear self-contained breathing apparatus (SCBA) with full protective gear to prevent contact with skin and eyes. Confine run-off to prevent environmental contamination. Approach fire from upwind.
Personal Precautions: Evacuate unnecessary personnel and ventilate affected area. Avoid breathing vapors, gas, or mist. Wear suitable protective clothing including gloves and goggles.
Environmental Precautions: Prevent entry into sewers, waterways, basements, or confined areas. Alert authorities if widespread contamination is likely.
Methods for Clean-Up: Absorb liquid spills with inert material (sand, earth, vermiculite), collect into suitable chemical waste containers. Wash spill area with detergents and sufficient water. Do not use combustible materials like sawdust for clean-up.
Handling: Work in well-ventilated areas, fume hoods preferred. Avoid inhalation and direct contact with eyes, skin, and clothing. Use explosion-proof equipment and prevent static discharge. Keep containers tightly closed when not in use.
Storage: Store in a cool, dry, well-ventilated location away from heat sources, direct sunlight, and incompatible substances like strong oxidizers. Keep container tightly sealed and upright. Store away from food and drink areas.
Exposure Limits: No occupational exposure limits established by OSHA, ACGIH, or NIOSH for this compound, use standard practices for hazardous volatile organics.
Engineering Controls: Provide exhaust ventilation or other engineering controls to prevent airborne concentrations from exceeding recommended limits. Fume hoods strongly recommended for laboratory use.
Personal Protective Equipment: Chemical resistant gloves (nitrile, neoprene), safety goggles with side-shields, face shield for splash potential, lab coat, long sleeves, and closed footwear. If ventilation is inadequate, use an air-purifying respirator with organic vapor cartridge.
Appearance: Clear, colorless to pale-yellow liquid
Odor: Slight, distinct, sweet-chlorinated odor
Odor Threshold: Not established
pH: Not applicable (non-water soluble liquid)
Melting Point / Freezing Point: -8°C
Boiling Point: 242–244°C
Flash Point: >110°C (closed cup method)
Evaporation Rate: Not available
Flammability: May present fire hazard; vapor may form explosive mixtures with air above flash point
Vapor Pressure: 0.047 mmHg at 25°C
Vapor Density: 6.2 (Air = 1)
Density: 1.07 g/cm³ at 20°C
Solubility: Insoluble in water, miscible with most organic solvents
Partition Coefficient (n-octanol/water): Log Pow 5.5
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not determined
Viscosity: Not available
Chemical Stability: Stable under normal temperatures and pressures. Storage in original containers at recommended conditions maintains shelf stability.
Reactivity: Reacts with strong oxidizing agents and may react violently with alkali metals. Decomposition can occur at elevated temperatures, producing hazardous byproducts such as hydrochloric acid.
Hazardous Polymerization: Will not occur under standard handling procedures.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon oxides
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: May cause headaches, nausea, cough, redness and burning of skin and eyes. Irritation to respiratory and digestive tracts if inhaled or swallowed. Central nervous system depression at higher concentrations.
Chronic Effects: Long-term exposure may affect liver or kidneys and increase sensitivity to solvents in general.
Toxicological Data: Oral LD50 (rat): ~2200 mg/kg; Dermal LD50 and inhalation limits not definitively established but expected to be in standard chlorinated hydrocarbon range.
Carcinogenicity: No direct evidence for carcinogenic activity in humans; not classified by IARC, NTP, or OSHA.
Mutagenicity and Teratogenicity: Not known to be mutagenic or teratogenic from available animal data.
Sensitization: Not reported in occupational cases at standard exposures.
Aquatic Toxicity: Toxic to aquatic organisms. May cause long-term adverse effects in the aquatic environment due to persistence and bioaccumulation.
Persistence & Degradability: Resistant to degradation in soil and water. Degrades slowly by hydrolysis and photolysis.
Bioaccumulation Potential: High; log Pow suggests strong tendency to accumulate in organisms.
Mobility in Soil: Low; adsorbs strongly to soil particles, limiting leaching but increasing persistence.
Other Adverse Effects: Discharge to the environment can affect aquatic wildlife, particularly amphibians and fish. Monitoring and controls for waste streams are necessary.
Waste Disposal: Dispose of in accordance with local, regional, national, and international legislation. Incineration in controlled facilities preferred. Contact licensed chemical waste disposal contractors.
Contaminated Packaging: Empty containers should be triple rinsed, punctured, and disposed of through hazardous waste collection systems.
Precautions: Avoid release to the environment. Prevent residues from entering drains, sewers, or natural waters.
UN Number: 3082
Proper Shipping Name: Environmentally Hazardous Substance, Liquid, N.O.S. (contains 1,8-Dichlorooctane)
Transport Hazard Class: 9 (Miscellaneous Dangerous Substances and Articles)
Packing Group: III
Environmental Hazards: Marine pollutant – ensure containment and labeling complies with IMDG/ADR/IATA guidelines
Special Precautions for Users: Avoid exposure during loading and unloading. Secure containers to prevent leaks and spills.
US Federal Regulations: Not specifically listed under TSCA, CERCLA, SARA Title III Section 313, or RCRA as of latest update, but may fall under generic hazardous waste codes and reporting for chlorinated organics.
EU Regulations: Subject to REACH registration; classified under CLP Regulation (EC) No 1272/2008 for acute toxicity and aquatic environmental hazard categories.
Labeling Requirements: GHS/CLP labels required for storage, transport, and handling.
Other Applicable Laws: Local regulations regarding chemical safety, reporting, and disposal of hazardous substances apply in every jurisdiction. Safety Data Sheets must be accessible to workers in regulated workplaces.
