Histry Chem

Conhecimento

1,8-Diaminooctane: A Down-to-Earth Commentary

Historical Development

Back in the early days of synthetic chemistry, scientists were eager to create molecules that could bridge the gap between long-chain hydrocarbons and reactive groups used in industry. 1,8-Diaminooctane emerged from this pursuit. Researchers found value in its straightforward structure: a straight, eight-carbon chain bearing amino groups at each end. By the middle of the 20th century, the chemical made its way from laboratory curiosities to production floors, largely because manufacturers needed flexible building blocks for developing polymers and specialty coatings. The simple structure attracted interest as a model compound in studying how primary diamines interact with various acids and resins. This led to increased understanding of how polyamides and polyurethanes could be tailored. That early research not only set the framework for today's applications, but also laid the foundation for safer handling and scalable production methods.

Product Overview

1,8-Diaminooctane, also called octamethylenediamine, exemplifies a practical, approachable intermediate. Its core value lies in its predictable reactivity—those two terminal amine groups can participate in a wide array of condensation and addition reactions. Industries appreciate that. You don't often see it on consumer labels, but its presence underpins the manufacture of polymers, curing agents, and surface modifiers. Factories receive it as a crystalline solid and count on its consistent performance, especially because it stores well, withstanding moisture to a reasonable degree in standard packaging. Its utility stretches into commercial coatings, adhesives, and even occasional pharmaceutical syntheses when unique linkages are required.

Physical & Chemical Properties

In my experience, few chemicals combine utility and straightforward handling as well as 1,8-diaminooctane. It appears as a white to slightly off-white crystalline material. Under normal conditions, it remains stable and non-volatile, with a melting point near 48°C and a boiling range that starts around 236°C. Its slight solubility in water makes cleanup less challenging compared to more viscous amines. The primary amine groups on both ends grant it significant nucleophilicity, driving its reactivity with many acids, anhydrides, and isocyanates. Though it releases a faintly fishy odor—a calling card of many aliphatic amines—ventilated facilities easily control this aspect. Its density sits around 0.86 g/cm³, which makes it manageable in either powder or granular form. In terms of chemical resilience, it stands up to moderate heat and diluted acids, but concentrated strong acids or oxidizers push it into less stable territory, so experienced operators take care.

Technical Specifications & Labeling

Manufacturers and distributors commit to clear specifications for the sake of downstream consistency. Typical commercial batches offer greater than 98% purity, with closely monitored levels of residual solvents or trace impurities. Color and melting point checks assure buyers they’re getting the intended substance. In practice, labeling highlights these attributes, along with hazard pictograms, recommended storage temperatures, and batch numbers for traceability. Correct UN number and danger signaling remain crucial for logistics, especially since larger shipments travel under regulatory oversight. This traceability supports both customer confidence and regulatory compliance, keeping supply chains trustworthy and minimizing the risk of mix-ups or mistakes during warehousing.

Preparation Method

The production route for 1,8-diaminooctane relies heavily on reliable and scalable chemical transformations. One well-established pathway begins with the hydrogenation of suberic acid dinitrile. Chemists first produce this dinitrile by dehydrating adipic acid, which itself traces back to petrochemical routes involving cyclohexanone. The final hydrogenation uses nickel or cobalt catalysts under moderate pressure and temperature, efficiently flooding the molecule with hydrogen to convert both nitrile groups into primary amines. The process creates a byproduct profile that safety teams monitor closely—chiefly ammonia and occasional trace amounts of unreacted starting material. Purification typically includes distillation or crystallization, yielding a product with the physical characteristics needed by end users. Facilities ensure robust containment and quality control checks at every stage, reducing chances for impurities that could compromise performance in downstream uses.

Chemical Reactions & Modifications

Among the family of diamines, this one stands out for its versatility in chemical synthesis. Those terminal amines react heartily with diacids, acid chlorides, and isocyanates, leading to lengthy polymer chains like polyamides or polyureas. In some settings, it blends with epoxides to form tough thermosetting networks, useful in high-performance coatings or adhesives. Functionalizing one end, for example through acylation, provides block copolymers with unique phase behavior. It’s hard to understate the value this brings—not only does it broaden the range of attainable material properties, but it also allows tuning of biodegradability, flexibility, and resistance to harsh environments. Formulation chemists push the boundaries by attaching varied side chains, building specialized surfactants or chelating agents for niche applications. The chemistry keeps expanding, with ongoing research into renewable feedstocks and green solvents that aim to shrink the environmental footprint of these syntheses.

Synonyms & Product Names

Finding references to 1,8-diaminooctane in literature or catalogs depends on knowing its other names. Octamethylenediamine remains the most frequently encountered alternative. Some chemical suppliers list it under the trade name OMDA, particularly in the polymer industry. Rarely, technical documents use the abbreviation ODA, though that can cause confusion with other diamines. For regulatory or customs paperwork, its CAS number, 373-44-4, removes any doubt about identity. Keeping tabs on these aliases can prevent ordering errors and support compliance with region-specific labeling and safety rules. It’s directly related to the structure—eight carbon atoms, each end capped with an amino group. This simplicity means careful readers can quickly cross-reference synonyms in technical specs or supplier documentation.

Safety & Operational Standards

Handling requirements for 1,8-diaminooctane reflect industry trends toward proactive safety culture. Workers must use gloves and eye protection because the pure amine can cause skin irritation, particularly with prolonged exposure. Inhalation of dust or vapor may lead to respiratory irritation, especially in enclosed spaces. Most operations include local exhaust ventilation and, for larger quantities, air monitoring. Spill protocols call for scooping up the solid and washing the area with copious water, since the amine neutralizes readily. Firefighters prioritize foam or dry chemical extinguishers, as burning diamines release nitrogen oxides. Facilities keep safety data sheets accessible at all points of use and provide first-aid training. Regulatory standards in Europe and the United States—such as REACH or OSHA—drive consistent hazard communication, periodic air monitoring, and emergency planning. Keeping up with these standards ensures not only legal compliance but also healthier work environments, where accidents and long-term risks fall to a minimum.

Application Area

The most important outlets for 1,8-diaminooctane spread across plastics and polymer manufacturing. Nylon variants and specialty polyamides depend on it to bring unique mechanical properties, such as enhanced flexibility or chemical resistance. In epoxy curing, its long chain and reactive ends produce networks that withstand stress and environmental exposure better than those using shorter or branched diamines. Surface treatment specialists employ the molecule to anchor coatings onto difficult substrates, including engineered composites and metals. Some pharmaceutical researchers tinker with it as a linker or protecting group, though these uses take a back seat to industrial scale consumption. Water treatment and mining sectors explore it in bespoke chelating agents, betting on its twin amines to nab metal ions. The widespread utility testifies to the flexibility of its molecular architecture—one small molecule opens doors across disparate industries, blending chemistry, engineering, and manufacturing know-how.

Research & Development

Scientists working in both private and public labs show no sign of slowing down innovation around 1,8-diaminooctane. Teams investigate bio-based production methods, seeking to move away from conventional petrochemical feedstocks. Catalytic upgrades, using milder and more selective reagents, catch a lot of interest due to environmental sustainability and cost reductions. Polymer chemists create new copolymers and blends that aim to reduce weight, improve recyclability, or provide antimicrobial properties—all by tweaking how 1,8-diaminooctane links into their backbones. Analytical advances give better insight into impurities or degradation products, helping teams clean up processes and extend shelf life. Universities and industrial partners cooperate on pilot-scale projects, aiming to bridge the gap between bench-scale success and warehouse-ready volumes. The healthy pace of patent filings and academic papers shows just how much life still bubbles up around this long-standing molecule.

Toxicity Research

Reliable data on toxicity shape every responsible discussion about industrial diamines. Comparable to other aliphatic diamines, 1,8-diaminooctane registers moderate irritation potential: it stings eyes and can redden skin after contact. Animal studies highlight that repeated exposure at higher concentrations brings organ effects, so manufacturers set conservative occupational exposure limits. The molecule breaks down fairly quickly in soil and water, thanks to microbial activity hungry for its nitrogen-rich chains—environmental fate studies back this up, reassuring regulators about risk outside manufacturing facilities. Toxicologists push to clarify potential reproductive effects and chronic health risks, especially as new uses move closer to food-contact or pharmaceutical settings. Transparency in reporting workplace incidents and open publication of test results matter, keeping all stakeholders—workers, neighbors, and downstream users—informed. The clear message from years of research: treat with care, but enjoy broad safety margins if handled as directed.

Future Prospects

Looking ahead, 1,8-diaminooctane seems poised for growth in role and value. Trends in lightweighting, demanded by both automakers and electronics producers, point toward advanced polymers that can’t function without precisely tuned diamine linkers. Interest grows in bio-renewable and biodegradable plastics, a field where adjusting chain length and reactivity using 1,8-diaminooctane promises fresh breakthroughs. Green chemistry thinkers explore alternatives to harsh solvents and energy-intensive processes, betting on catalysts and renewable feedstocks to shrink both costs and environmental impact. Regulatory certainty—supported by decades of consistent safety data—keeps investment steady. Customers expect transparency, traceability, and compliance as basic features, not extras. With emerging demand in advanced coatings, specialty adhesives, and next-generation composites, the chemical world leans on innovation and responsible stewardship to steer this venerable molecule into new territory.



What are the primary uses of 1,8-Diaminooctane?

Breaking Down What 1,8-Diaminooctane Really Does

1,8-Diaminooctane pops up in discussions around specialty chemicals, especially in research circles and advanced industries. At its core, this compound anchors several important processes in both lab and manufacturing settings. You’ll find it in the formula for polyamides and polyimides—types of plastic that engineer strong, durable end products. With experience in materials science labs, I’ve seen how even small differences in chemical building blocks can change the final material’s performance. 1,8-Diaminooctane brings both flexibility and toughness to the table, qualities needed in gears, films, and insulation that must last under pressure.

Synthetic chemists often reach for this diamine when they’re looking to create long molecular chains with specific spacing between amine groups. Spacing matters a lot in chemistry. Too crowded, and the molecules tangle up in ways that reduce strength. Too loose, and the structure breaks down easily. 1,8-Diaminooctane lands in that sweet spot, which lets scientists fine-tune polymers for items like automotive parts and electronics. Solid-state batteries now attract a lot more attention, and many electrolyte designs rely on these types of compounds for both stability and flexibility.

More Than Just Plastics—Diving Into Other Applications

The pharmaceutical sector uses 1,8-Diaminooctane as a linker or reagent in producing complex molecules. This is not a front-page headline, but people who build new drugs know that every tailored length between functional groups makes or breaks a synthesis plan. Medicinal chemists see value in octamethylene spacing. In my own experience working with organic synthesis teams, I saw them reach for this diamine when nothing else would give the right pocket size for a targeted molecular structure.

Little details mean a lot in biotech too. Crosslinking agents like 1,8-Diaminooctane help bond proteins to sensor surfaces or medical devices, which increases sensitivity in diagnostic tests. Biosensor engineers—especially those working with immunoassays or enzyme electrodes—count on this diamine to tie their biological recognition elements onto solid supports without losing activity. A robust biosensor makes a direct impact on disease detection, allowing clinicians to diagnose faster with smaller samples.

Challenges and Roadblocks

Anyone who works with 1,8-Diaminooctane knows about its handling headaches. It carries some toxicity, and breathing in the vapors can rapidly irritate the eyes or lungs. Strict lab safety rules are essential. PPE isn’t a checklist item; it’s a necessity. Spills and accidental skin contact require immediate response. Regulatory guidelines already lay out storage and usage limits, but there’s always room for better education across sectors—especially mixing or handling teams in factories.

Waste disposal brings another layer. Unused or spent 1,8-Diaminooctane demands careful treatment. Down the drain is never an option. Incineration or chemical deactivation lines up better with current environmental standards. Any facility using such substances should train workers thoroughly, not just hand out a data sheet.

Moving Forward

Better safety technologies and greener synthesis methods give hope for simpler, lower-risk use in the future. Innovators in chemical manufacturing continue to test less hazardous alternatives as crosslinkers or spacers, aiming to keep the same properties without the danger tags. From my perspective in research, nothing beats working with a substance that brings performance and peace of mind. Ongoing open-source data on exposures and environmental effects will help everyone along the chain—researchers, workers, and end users—make informed decisions about how they work with 1,8-Diaminooctane and what should replace it in the years ahead.

What is the chemical formula and structure of 1,8-Diaminooctane?

Chemical Formula and Structure

Whenever someone picks up a container labeled 1,8-diaminooctane, they’re handling a molecule that packs a simple punch: its formula is C8H20N2. Each molecule has eight carbon atoms strung together in a chain. At both ends of this chain, you’ll find an amino group, which is a nitrogen atom attached to two hydrogens. If you looked at it drawn out, it would show as H2N-(CH2)8-NH2, with the “octane” hinting at those eight carbons in the backbone. It’s straightforward, but those two ends matter more than they seem.

Why Structure Matters to Chemists

Back in the lab, simplicity like this always has a payoff. 1,8-diaminooctane works almost like a bridge. It reaches out from one end with a reactive group and extends to the other, making it an excellent chain extender or linker in making complex polymers. I remember a project years ago where this sort of diamine was critical for forming certain types of nylon. With two amino groups spaced far apart, the resulting polymers end up with extra flexibility and useful mechanical properties—tough enough for engine parts, yet smooth enough for fibers in clothing.

Reactivity and Practical Usage

People often overlook just how reactive those terminal amines can be. The molecule reacts with acids to form salts, it bonds easily with aldehydes and ketones, and it hooks onto isocyanates for making polyurethanes. In one of my old projects, I saw how these characteristics let a team design more resilient adhesives for electronics housings. Instead of failing after a few cycles of heating and cooling, the joints lasted through season after season. There’s trust in a solution when you know the starting materials brought such backbone to the table.

Safety and Handling Concerns

Decent chemistry always respects potential hazards. 1,8-Diaminooctane can be an irritant. It smells a bit fishy, and any splash risks a burning sensation, so gloves and goggles weren’t optional on those days mixing it into blends. The Material Safety Data Sheet lists it as hazardous to eyes and skin, and it doesn’t take much to learn that lesson firsthand. Proper ventilation in the lab made everyone breathe easier. Strict protocols and proper storage kept incidents rare—simple steps go a long way in making chemistry sustainable.

Impact on Industry and Research

Lots of the products people rely on get their performance from modest molecules like this one. Nylon and polyurethane owe much of their durability and resilience to choices at the building block level. From car dashboards to medical tubing, these long chains, built in part by diamines like 1,8-diaminooctane, end up shaping real-world products. The research keeps moving forward—scientists now look at greener ways to manufacture and recycle such diamines, driving toward a less wasteful chemical industry. Cutting reliance on harsh solvents and shifting to renewable feedstocks means the next generation of engineers can keep using these critical tools, but with one eye on the planet.

How should 1,8-Diaminooctane be stored and handled safely?

Why Storage and Handling Matter

1,8-Diaminooctane doesn’t look imposing. It’s a white, crystalline powder that refuses to draw much attention in a lab. Anyone who has spent time with chemicals knows appearances rarely mean much. Hazards don’t advertise themselves, and 1,8-Diaminooctane is no different. With sufficient contact or careless storage, this simple powder can provoke skin irritation, respiratory stress, or worse. Sticking to strong safety habits, learned from long afternoons in small, busy storerooms, makes the difference between a manageable risk and an accident that lingers on the record or in your memory.

Proper Storage Keeps People Healthy

Every facility that stores chemicals has its tales of mix-ups, awkward labels, or dramatic cleanups. Locking down a process that respects what each substance can do matters most. 1,8-Diaminooctane prefers a cool, dry, well-ventilated spot. Humidity eats away at the integrity of the powder, making clumps that stick together or release fumes. A tightly sealed container—glass or compatible plastic—shuts out stray moisture. Containers always stand upright away from heat sources or sunlight. Shelves stocked with clear, sturdy labels cut through the confusion any busy worker faces during a shift.

Small Steps, Big Impact

Some folks look at glove requirements on the safety sheet and ignore them. It’s easy to think, “It’s just a little powder.” From my years in the lab, I saw more hands than I care to remember, chapped and cracked from dodging such instructions. Nitrile gloves defend against both the sting and possible absorption of the substance through bare skin. Lab coats stand between clothing and a persistent odor that never washes out.

Eye protection keeps tiny dust particles out of the tear ducts. Face shields help during weighing or pouring. Splash goggles leave less of the face exposed. No one remembers to work near an eyewash station until it’s too late. Once, during a late-night inventory, a colleague got a dusting in the face and scrambled blindly to the wash. He’d memorized the route during safety drills. That habit saved his vision.

Vigilance During Handling

Working in a fume hood, not at a regular bench, limits inhalation of vapors or airborne powder. Spills belong in the hands of someone trained, with spill kits stationed within reach, not buried three rooms away. No food or drinks linger anywhere chemicals live. It sounds obvious, but old habits die hard.

Every container returns to its place, lid snapped shut, after each use. Open containers attract trouble. Keeping inventories up to date, logging each withdrawal, and inspecting for leaks earns a few groans but heads off nasty surprises down the line.

Solving Storage and Handling Hazards

Talk among team members about problems or near-misses creates a network of shared caution. Routine drills on spill response, regular audits of storage areas, and honest feedback rebuild trust when things go well and highlight where they don’t. Hospitals, universities, and industry labs benefit from connecting with their supply chain, checking expiry dates, and never storing chemicals by hazard class alone. Sticking notes or reminders at eye level crowds out routine forgetfulness.

Clear instructions combined with practical experience stand guard against a relaxed attitude. Chemicals like 1,8-Diaminooctane won’t lead to excitement or headlines. It’s quiet, systematic discipline—putting safety first every single time—that holds everything together.

What are the potential health hazards of 1,8-Diaminooctane?

Exposure Risks in Everyday Settings

1,8-Diaminooctane doesn’t show up on consumer product labels, but it plays a quiet role in the world of industrial chemistry. Used to make specialty plastics and coatings, this compound handles a lot of heavy lifting in the background. Yet, when workers handle or manufacture it, health concerns can pop up pretty quick. During one of my stints at a manufacturing plant, I saw how fumes can sting the eyes or throat if protective gear goes ignored.

Possible Symptoms From Exposure

Strong chemical smells give away 1,8-Diaminooctane. Direct contact with skin can cause redness or even a burn-like feeling in some people. Breathing in its vapor might trigger headaches, trouble breathing, or even nausea. One of my old colleagues complained about feeling short of breath after a bad spill, even though he thought he had good ventilation in his work area. Eyes take the brunt, too; splashes can lead to watery, irritated eyes or blurred vision.

Health agencies like the National Institute for Occupational Safety and Health classify amines as potential respiratory sensitisers. Over time, continued exposure, even at levels that don’t feel dramatic, can lead to asthma-like symptoms or increased sensitivity to smells. Reports also describe cases of skin rashes and even chemical burns from repeated contact.

What Science Tells Us About Long-Term Health

Long-term risk sits at the heart of industrial exposure. Studies on compounds with similar structures suggest repeated, long-term contact increases the odds for chronic dermatitis and respiratory issues. Animal studies—used as models for what might happen in a human—show damage to the liver and kidneys after high-dose exposures. Research remains limited, so we don’t know if 1,8-Diaminooctane causes cancer, but chemicals in its class often raise red flags for possible DNA damage.

Most public health guidelines recommend keeping this compound contained or handled under strict conditions. Material safety data sheets make the dangers clear, pressing for regular air monitoring, emergency showers, and careful waste disposal. I always tell anyone new to industrial work: never treat these recommendations like background noise, because one mistake can change how your body works for years to come.

What Can We Do About It?

Prevention outpaces treatment every time in these situations. In shops and plants, wearing chemical-resistant gloves, goggles, and masks stands as the gold standard. Employers should swap out regular exhaust fans for advanced fume hoods or local ventilation. I’ve seen teams bring in air-quality sensors that beep as soon as vapors begin to creep above safe levels, which gives people a chance to clear out before symptoms take hold.

Training forms a second line of defense. Walking through safety drills and learning how to clean spills can prevent freak accidents. For those curious about household risks: 1,8-Diaminooctane barely slips into consumer spaces. The real hazards fall on folks handling it head-on—chemists, plant workers, or emergency crews. Everyone else stays pretty safe unless storage or shipping accidentally fails.

The Big Picture

1,8-Diaminooctane shows how an important industrial tool can quickly flip into a hazard if mishandled. Paying attention to symptoms, sticking to safety protocols, and staying up to date on new research protects both workers and their families. Good science and common sense go hand in hand, especially when health stays on the line.

Is 1,8-Diaminooctane available in various purities or grades?

Purity Never Strikes as Uniform: The Straight Facts

Every chemist recognizesthe struggle in sourcing 1,8-diaminooctane with the right purity for any job. Lab work never gives you clean answers, and that proves especially true for chemicals like this. Walk into any lab supply room, and there’s almost always another shelf of bottles with wildly different labels — something called “technical,” maybe “analytical,” sometimes “reagent,” or even “high-purity grade.” Each label tells a story about how carefully contaminants get kept out. For people working in polymer synthesis or specialty coatings, that story matters more than they’d like to admit. Even in undergraduate teaching labs, purity quirks can make or break a day’s results.

When manufacturers prepare 1,8-diaminooctane, the cost and effort needed for extra purification stack up pretty fast. Some brands claim over 99% pure. That number can look convincing, but small traces of unknowns creep in unless the process gets strict.

Why This Matters More Than It Appears

I used to help run a university research group, and price often sat at odds with purity. We would see quotes for 98%, 99%, or “ultra” pure. Nobody dared pick the wrong one, since just a sliver of another amine or a speck of water could upend a whole synthesis. One time, a batch of monomer didn’t cure correctly—it all traced back to the nitty-gritty of impurity levels. Someone saved fifty dollars upfront, but lost weeks of work in the end. It doesn’t always come down to visible outcomes, either. Even when the final polymer passed appearance checks, hidden issues sometimes emerged in mechanical properties and batch stability. Actual purity trickles through every step, so the grade you see on a bottle becomes a lever for the project’s success.

On the industrial side, producers feel the same headache. Soft packaging or adhesives demand high standards, or else product returns start piling up. One missed impurity causes a string of warranty complaints. For people pushing for safety and medical grades, there’s little room for error. This brings traceability and full documentation front-and-center. An “off-the-shelf” solution might work in teaching, but deeper use calls for a direct relationship with suppliers and sometimes third-party testing.

Factoring Risk: Not All Grades Suit All Jobs

The workhorse chemicals market rarely holds surprises for folks in the business, but 1,8-diaminooctane keeps reminding teams that purity calls the shots in performance. Research from the past two years shows that material properties in advanced polymers drop quickly as the level of side products rises, especially if they build up in each production lot. That’s not just academic talk. Health and safety compliance often depends directly on these small numbers in the SDS sheet, and regulators have started taking notice as polymer supply chains hit the news.

To break the cycle, more labs now test each lot on arrival rather than just trusting supplier paperwork. Some standard tests, like HPLC or Karl Fischer titrations, catch low-level water or amine impurities even after the bottles leave the factory. Others ask for samples, run their own checks, and compare notes. That hands-on control keeps surprises to a minimum and lets teams react quickly if something feels off.

Lessons From the Field: Asking the Right Questions

Everything always comes back to purpose. Before your next order, ask not just, “Is this pure enough?” but, “What am I willing to risk if it isn’t?” Trade-offs between price and grade come with the territory, but experience shows that full visibility into what’s inside each batch beats gambling with results. It takes more oversight, but that’s the price of fewer headaches down the road.

1,8-Diaminooctane
1,8-Diaminooctane
1,8-Diaminooctane
Names
Preferred IUPAC name octane-1,8-diamine
Other names Octamethylenediamine
Octane-1,8-diamine
Pronunciation /waɪt əˌmiːnoʊ ˈɒkteɪn/
Identifiers
CAS Number 373-44-4
Beilstein Reference 1433103
ChEBI CHEBI:32810
ChEMBL CHEMBL48857
ChemSpider 75001
DrugBank DB01996
ECHA InfoCard echa.europa.eu/infoCard/100.003.425
EC Number 211-162-9
Gmelin Reference 83233
KEGG C01803
MeSH D000069
PubChem CID 8717
RTECS number RO2275000
UNII AX32B8R6WA
UN number UN2284
CompTox Dashboard (EPA) DTXSID0021775
Properties
Chemical formula C8H20N2
Molar mass 144.28 g/mol
Appearance Colorless to pale yellow liquid
Odor amine-like
Density 0.871 g/mL at 25 °C
Solubility in water Slightly soluble
log P -0.6
Vapor pressure 0.02 mmHg (25 °C)
Acidity (pKa) 10.85
Basicity (pKb) 3.36
Magnetic susceptibility (χ) -55.7·10⁻⁶ cm³/mol
Refractive index (nD) 1.462
Viscosity 17.1 cP (20°C)
Dipole moment 3.05 D
Thermochemistry
Std molar entropy (S⦵298) 311.8 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -117.2 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -4636.7 kJ/mol
Hazards
Main hazards Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
GHS labelling GHS02, GHS07
Pictograms GHS07
Signal word Warning
Hazard statements H302, H315, H319, H334
Precautionary statements Precautionary statements: P261, P280, P305+P351+P338, P310
NFPA 704 (fire diamond) 1-2-0
Flash point 113 °C
Autoignition temperature 355 °C
Explosive limits Explosive limits: 0.7–5.0%
Lethal dose or concentration LD50 oral rat 1240 mg/kg
LD50 (median dose) LD50 (median dose): 1200 mg/kg (oral, rat)
NIOSH UR8225000
PEL (Permissible) Not established
REL (Recommended) 1,8-Diaminooctane,99%
IDLH (Immediate danger) IDLH: 15 mg/m3
Related compounds
Related compounds Hexamethylenediamine
Octamethylenediamine
Putrescine
Cadaverine