Product Name: 1,6-Hexanediol
Other Names: Hexane-1,6-diol, HDO
CAS Number: 629-11-8
EC Number: 211-074-0
Recommended Use: Intermediates in the production of polyesters, polyurethanes, coatings, plasticizers, adhesives
Manufacturer: Company contact information, including address, phone, and emergency number, must be included for user reference.
Emergency Contact: Chemtrec or company-designated emergency hotline
UN Number: Not classified as dangerous goods under UN recommendations.
Classification: Not classified as hazardous according to GHS standards in most jurisdictions; avoids labeling requirements for toxic or flammable content
Label Elements: Usually does not require pictograms or signal word for transport, trading, or daily use
Main Hazards: Can irritate eyes and skin; inhalation of dust can cause respiratory discomfort; ingestion can bring abdominal pain, headache, or nausea
Environmental Hazards: Large spills can lead to oxygen depletion in bodies of water, but persistence or bioaccumulation remains low
Precautionary Statements: Avoid direct contact with skin, eyes, and clothing; prevent dust buildup; ensure adequate ventilation; follow good hygiene.
Chemical Name: 1,6-Hexanediol
Synonyms: Hexamethylene glycol, HDO
CAS Number: 629-11-8
EC Number: 211-074-0
Formula: C6H14O2
Percentage: Pure 1,6-Hexanediol comprises at least 99% of the product by weight.
Impurities: Trace water and minor organic byproducts from production, all below 0.5%.
Inhalation: Move the person exposed to fresh air; if symptoms like coughing or breathlessness present, seek medical advice
Skin Contact: Remove contaminated clothing and wash affected skin thoroughly with soap and water
Eye Contact: Rinse the eyes gently with plenty of running water for at least 15 minutes; lift eyelids repeatedly to clear any trapped material; acquire medical attention if irritation persists
Ingestion: Rinse mouth with water; never induce vomiting unless directed by medical personnel; if symptoms remain or the person feels unwell, pursue medical attention
General Advice: Always get prompt medical support for longer-lasting symptoms or large exposures.
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, and carbon dioxide all curb the spread of fires fueled by 1,6-Hexanediol
Special Hazards: Decomposition releases carbon monoxide and carbon dioxide during intense heat; dust from handling can explode in air under some conditions
Protective Equipment: Firefighters should equip themselves with full protective clothing and self-contained breathing gear
Advice for Firefighters: Avoid breathing smoke or fumes; cool intact containers with water jets from a safe distance
Personal Precautions: Limit exposure by wearing gloves, protective eyewear, and suitable clothing; clear unnecessary personnel from the area
Environmental Precautions: Contain spilled material to keep it away from drains and waterways
Clean-up Methods: Gather spill using non-sparking tools; transfer to appropriate, labeled waste containers; wash contaminated area with water to dissipate residue
Emergency Procedures: Large spills require local authorities' input and professional hazardous waste contractors
Handling: Use only in well-ventilated spots; ground all equipment to cut down static discharge risk; avoid formation of dust clouds; never eat, drink, or smoke during handling
Storage: Store in tightly closed, original containers away from any heat or sources of ignition and sunlight; position above incompatible substances like strong oxidizers and acids; stable between 2°C and 40°C
Recommended Storage Materials: Polyethylene, stainless steel, or coated steel drums and tanks; avoid containers susceptible to corrosion or that will degrade on contact.
Occupational Exposure Limits: No current established limits for 1,6-Hexanediol in most regions
Engineering Controls: Mechanical ventilation systems lower dust and vapor concentrations; local exhaust at points of dust or vapor release
Respiratory Protection: NIOSH-certified masks or respirators only necessary when dust or mist exceeds recommended exposure levels
Skin Protection: Chemical-resistant gloves, long sleeves, and protective aprons
Eye/Face Protection: Safety goggles or face shields guard against splashes and airborne dust
Hygiene Measures: Wash hands before eating, drinking, and after work; keep work clothes separate from home laundry to prevent home contamination
Appearance: White, waxy solid (sometimes available as colorless needles)
Odor: Faint, sweet
Melting Point: 42 – 45°C
Boiling Point: 250°C (at atmospheric pressure)
Flash Point: 137°C (closed cup, indicative of low fire risk under normal conditions)
Vapor Pressure: Less than 0.01 hPa at 20°C
Solubility: Completely soluble in water and alcohols
Density: 1.12 g/cm3 at 20°C
Partition Coefficient (log Kow): -0.02, signifying limited potential for fat accumulation in living tissue
Explosive Properties: Fine dust generated during processing can explode in air under high concentrations
Auto-Ignition Temperature: 375°C
Chemical Stability: Stable under normal temperatures and recommended storage conditions
Hazardous Reactions: May react with strong oxidizing agents, acids, and acid chlorides
Conditions to Avoid: Excessive heat, flame, and sources of ignition amplify fire risk through dust or decomposition
Incompatible Materials: Strong oxidizers, nitric acid, and organic peroxides catalyze decomposition
Hazardous Decomposition Products: Burning produces carbon monoxide, carbon dioxide, and small amounts of irritating organic vapors
Acute Toxicity: Oral LD50 in rats falls in the range 2000 to 5000 mg/kg, showing low acute oral toxicity
Skin Irritation: Can provoke mild irritation with extended or repeated contact
Eye Irritation: Direct contact causes stinging and redness
Respiratory Sensitization: Inhaled dust may irritate upper airways and lungs; chronic effects seldom reported
Carcinogenicity: No link to cancer development, backed by animal evidence and absence from NTP, IARC, ACGIH lists
Reproductive Toxicity: No evidence of effect on fertility or development
Chronic Exposure: Prolonged or frequent skin contact may lead to eczema, dermatitis, or mild allergic reaction in some sensitive individuals
Ecotoxicity: Minimal acute or chronic effects on aquatic life, largely handled in wastewater treatment plants
Persistence and Degradability: Biodegradable by standard environmental processes; rapidly and completely breaks down in soil and water
Bioaccumulation: Low potential for accumulation in organisms or along food chains
Mobility: Dissolves easily in water, can be mobile in surface and groundwater
Aquatic Toxicity: LC50 for freshwater fish higher than 100 mg/L, indicates low hazard under usual use
Other Effects: Depletes oxygen if present in large quantities; no significant risk of long-term toxicity or habitat disruption noted
Product Disposal: Handle as industrial waste; incinerate or treat at approved hazardous waste facility; never release bulk quantities into surface waterways or sewage systems
Container Disposal: Rinse used packaging thoroughly, scrap or recycle according to local and national regulations
Special Instructions: Consult local authorities for code-compliant disposal methods tailored to chemical waste; always record volume and nature of disposed material for audit and traceability
Decontamination: Remove and properly treat residue from containers before sending for reuse or landfill
UN Number: Not regulated for road, rail, air, or sea
Proper Shipping Name: Not formally assigned due to non-hazardous status
Transport Hazard Class: Not applicable
Packing Group: None
Environmental Hazards: Not a marine pollutant
Special Precautions: Prevent spillage during transit; use robust containers approved for chemicals to avoid breaking, leaking, or accidental release.
Labeling Requirements: Ordinary labels suffice, no pictograms or hazard symbols legally necessary for routine use
Global Inventories: Registered in chemical inventories including TSCA (USA), EINECS/REACH (EU), DSL (Canada), ENCS (Japan), AICS (Australia), KECI (South Korea)
OSHA Regulation: Not classified as a hazardous substance
SARA Title III: Not listed under sections for acute or chronic hazard; reporting threshold not triggered
REACH Registration Number: Stated by producer on request for compliance tracking
Other Standards: Absent from California Prop 65; not subject to additional toxin, carcinogen, or heavy metal restrictions in major global markets
