Product Name: 1,2,4-Butanetriol
Chemical Formula: C4H10O3
Synonyms: 1,2,4-Butanetriol; Butane-1,2,4-triol
CAS Number: 3068-00-6
Recommended Use: Intermediate in chemical synthesis, explosives, plastics, and pharmaceuticals
Supplier Details: Supplier information and emergency contact numbers noted by chemical distributors and manufacturers
Emergency Contact: Refer to country or region-specific poison centers or the company emergency line where materials are sourced
Classification according to GHS: Not classified as hazardous under GHS standards
Label Elements: No pictogram required; Not considered a hazardous substance or mixture
Hazard Statements: May cause mild irritation to eyes, skin, and respiratory membranes upon direct or prolonged exposure
Precautionary Statements: Handle using basic hygiene and laboratory safety procedures
Routes of Exposure: Skin contact, eye contact, inhalation, accidental ingestion
Symptoms: Redness, mild irritation, coughing if vapors are produced at elevated temperatures
Chemical Name: 1,2,4-Butanetriol
Concentration: 98%–100% pure
CAS Number: 3068-00-6
Impurities: Water, trace organics (<2%)
Other Components: No significant stabilizing agents or additives
Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse exposed area with water and gentle soap, get medical help for persistent irritation
Eye Contact: Immediately flush eyes with water for at least 15 minutes, keep eyelids open, contact eye specialist if irritation continues
Ingestion: Rinse mouth thoroughly, drink water if able, do not induce vomiting unless directed by a medical professional; call poison center
Notes for Medical Staff: Treat based on symptoms, no specific antidote known
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Avoid use of high-pressure water jet due to risk of spreading contaminants
Specific Hazards: Vapors may form combustible mixtures in air if heated; thermal decomposition can release carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective gear
Firefighting Instructions: Cool fire-exposed containers with water spray, contain runoff to prevent environmental contamination
Personal Precautions: Wear gloves, eye protection, appropriated protective clothing
Environmental Precautions: Prevent release into soil, surface water, and drains; contain spillage with inert absorbent material
Spill Clean-Up Procedures: Absorb with sand, earth, or commercial absorbent; place material in chemical waste container; ventilate area
Decontamination: Wash area thoroughly with water and mild detergent after removal of bulk material
Handling: Use in well-ventilated workspaces; avoid inhaling vapors or mist; prevent contact with eyes and prolonged contact with skin; keep containers tightly closed
Storage Conditions: Store in original, labeled containers at room temperature away from direct sunlight and heat sources; keep away from strong oxidizers
Shelf Life: Maintain in controlled environment for best stability; avoid exposure to moisture and air to reduce risk of degradation
Technical Measures: Use local exhaust ventilation in large-scale applications; maintain good hygiene practices
Occupational Exposure Limits: No specific limits set by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation and general dilution ventilation
Personal Protective Equipment: Safety glasses with side shields, chemical-resistant gloves, lab coat or apron
Respiratory Protection: Not required under normal conditions; use NIOSH-approved respirator if airborne concentrations rise through handling large volumes at elevated temperatures
Hygiene Measures: Wash hands and face before eating, drinking, or smoking; remove contaminated clothing and clean before reuse
Appearance: Clear, odorless, viscous liquid
Molecular Weight: 106.12 g/mol
Boiling Point: 274–280°C
Melting Point: 18–22°C
Solubility: Miscible with water, alcohols, and many organic solvents
Vapor Pressure: Very low at ambient temperatures
pH: Neutral (about 7 in 50% aqueous solution)
Flash Point: Above 120°C (closed cup)
Autoignition Temperature: Not available
Odor Threshold: Odorless or very faint sweet odor
Chemical Stability: Stable under recommended storage and normal temperatures
Reactivity: Not expected to react under normal conditions
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: Combustion produces carbon oxides; no other hazardous products expected
Conditions to Avoid: Prolonged exposure to humidity and high temperatures
Acute Toxicity: Low toxicity based on animal studies; oral LD50 (rat) estimated about 4,000 mg/kg
Skin Corrosion/Irritation: Mild, temporary irritation in sensitive individuals
Eye Damage/Irritation: Mild irritation based on animal testing
Respiratory or Skin Sensitization: No evidence of skin sensitization
Carcinogenicity: Not recognized as a carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity: Not known to be mutagenic
Reproductive Toxicity: Not reported in available literature
Repeated Dose Toxicity: Long-term exposure data limited; not expected to produce organ toxicity in industrial scenarios
Other Effects: Large quantities may worsen pre-existing liver, kidney, or respiratory conditions if repeatedly ingested or inhaled in vapor form
Ecotoxicity: Practically non-toxic to aquatic life at levels used in commerce; data suggests LC50 for fish is high >100 mg/L
Persistence and Degradability: Readily biodegradable in soil and water by microbial action
Bioaccumulation: Low bioaccumulation potential based on octanol-water partition coefficient (log Kow < 0)
Mobility in Soil: High mobility; fully miscible in water allows for easy movement through soils if released
Other Adverse Effects: No evidence of significant chronic impact at typical discharge concentrations
Waste Treatment Methods: Collect and place in suitable containers for chemical waste; dispose by incineration at approved facility or by local requirements
Container Disposal: Rinse empty containers, render unusable, and dispose or recycle according to local regulations
Disposal Precautions: Prevent chemical from entering drains or waterways; follow regional, national, and local regulations for chemical disposal
Special Instructions: Small amounts may be diluted and sent to sanitary sewer with copious water, if permitted by local authorities
UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Handle with the same care as any industrial chemical; avoid leaks and spills during transit; ensure appropriate labeling and secure packaging
Environmental Hazards: None under normal use and transport conditions
Chemical Inventory Status: Listed on TSCA (USA), EINECS (EU), DSL (Canada), and comparable inventories in major jurisdictions
OSHA Status: Not regulated as a hazardous chemical under the Hazard Communication Standard
SARA Title III: Not a designated hazardous substance
California Proposition 65: Not listed as a substance known to cause cancer or reproductive toxicity
REACH Status: Registered or exempted in the EU under REACH regulation
Other Regulations: End users should review regional and local rules for environmental release, workplace exposure, and safe handling
